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COVID: Third Dose Vaccination Increases 3-5 Folds To Neutralize Antibody Titers

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KUALA LUMPUR, Aug 20 — A third dose of COVID-19 vaccine, given at an interval of six months after the second dose, can lead to a strong boost in immune response, with an increase of three to five folds in neutralising antibody titers.

Pharmaniaga Berhad vaccine specialist Dr Ajit Pal Singh Raina said the results from a recently completed immune-persistence study of Sinovac demonstrated that two doses of CoronaVac COVID-19 vaccine induced good immunogenicity.

He said although neutralising antibody levels declined after six months, a two-dose vaccination schedule generated a strong immune memory.

“Hence, will a booster shot be necessary? The third dose of CoronaVac effectively boosts neutralising titers and provides a better immuno-protection response. This pattern is consistent with other vaccines like AstraZeneca, showing higher concentrations of total Immunoglobulin G (IgG) antibodies after a third dose.

“It is also worth mentioning that timing for a booster dose is critical and not to be given too early,” he was quoted as saying in his article for Thoughts published at Bernama news portal today.

Immunogenicity or neutralising antibody titers is defined as the ability to provoke an immune response capable to kill or neutralise virus causing disease, he said, adding that it would result from the bio-material being detected by the body’s immune system as a foreign object and the body’s response to eliminate it with the use of neutralising antibodies.

Citing the University College London (UCL) researchers, he said decay in Antibody titers would also be seen with other COVID-19 vaccines where antibody levels start declining from as early as six weeks after complete vaccination with Pfizer and AstraZeneca vaccines.

He said the antibody reduced further by more than half in 10 weeks, confirming the need for a booster dose.

The findings were published as a research letter in The Lancet, which are based on data from over 600 vaccines.

“However, different methods and measuring units are used to measure decay at the antibody level, hence, the results are not directly comparable but indicate a similar decline in antibodies overtime for all vaccines.

“After initially spurning the idea of booster dose and complete understanding of how the vaccine works against COVID-19 virus, it is clear from recent studies that protection from severe disease and hospitalisation remain high after vaccination.

“However, the surge in cases caused by the contagious and deadly variants have caused some countries to look more closely at booster shots, and some have even started administering them,” he added.

Sources: BERNAMA

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(Video) Here’s What Really Happens If You Only Drank Coke

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Coke is actually a carbonated soft drink manufactured by famous The Coca-Cola Company. It was invented in the late 19th century by the one and only John Stith Pemberton and was bought out by businessman Asa Griggs Candler, whose marketing tactics led Coca-Cola to its dominance of the world soft-drink market throughout the 20th century. The particular drink has inspired imitators and also created a whole classification of soft drinks. So many selections.

It can do some pretty strange things. And the ingredients inside of it might be even more bizarre. Just imagine what it’s doing inside your body after you drink it. Can you imagine only drinking Coca-Cola for the rest of your life? The effects that the soft drink called Coke brings to your body would be so surprising. How bad would coke affect humans?

A single can of Coke has 39 g of sugar. To get your daily fluid intake, you would need to drink over eight cans of Coke each day. That is 312 g of sugar. It would be a lot of extra sugar, not to mention the extra calories. Coke intake alone would be nearly an extra 8,000 calories a week. But that would not be all. There are actually a lot more health issues.

This sugary drink could also cause you to eat more as well. And with all these extra calories, it would lead to some serious weight gain. As you drink more Coke, tooth decay would also be a severe issue. Each sip of Coke would coat teeth, tongue, and gums for hours after you’ve finished your soda. The sugars would slowly break down your enamel.

One of the main ingredients you’d need to worry about is high fructose corn syrup. That’s because our bodies do not metabolize it. This could lead to a fatty liver. Symptoms of a fatty liver include fatigue and pain in the upper right abdomen. Due to all the sugar, caffeine, and others, you would also experience a lot of problems with your heart rate.

As time goes on, you would also have a massive risk of getting Type 2 diabetes, and loads of vitamin deficiencies. And if all these issues continued, and you decided to ignore them, you could develop proteinuria, which could then lead to kidney problems. That is why it is better to just save drinking Coke as a treat rather than to have it every day in life.

Sources: YouTube The Infographics Show, YouTube AsapSCIENCE.

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Book Review: Perfect For Teachers, ‘Chicken Soup For The Teacher’s Soul’ Book

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As a teacher, teaching is an important and rewarding career, but it can also be draining and exhausting. Teaching is arguably harder now than ever before for many reasons, including student behavior, rapidly changing technology, and low pay. That is why teachers from all over the world needed some pick-me-up stories that they can read to help.

In this book, it states that most people recall a teacher or two who had a significant impact on their future. In fact, outside the family unit, teachers have more influence on our lives than anyone else. Good teachers help students believe in themselves with a glimpse of what they might become. They go the extra mile to make learning fun and meaningful, they inspire students to dream and broaden their horizons. Teachers have the power to change lives.

Picture: Book Depository

Reading this particular book, readers will surely laugh and also cry along with these stories from educators of all ages. Other than that, the book talks about the kids who affected them most deeply, their personal ups and downs as teachers, their funniest moments, their most heartwarming experiences, and lots of great tips for the classroom.

The stories included are touching, fun, and very relatable. This book makes a great gift for any teacher who likes to read. It may also be a good read for parents to get an inside look at the life in the day of teachers. This book is so inspirational. The stories in the book really help the readers to be able to feel rejuvenated again and remind them why then become a teacher. It is such a good book to have around for those days that you need that little reminder.

Sources: Chicken Soup.

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(Video) Try These 7 Tips That Can Help You Have A Good Night’s Sleep

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According to facts, adults need in total of 7-9 hours of sleep each night to stay in good mental and physical health, promote quality of life, and also avoid an increased risk of injury. If you are someone who keeps on thinking about all of the factors that can interfere with a good night’s sleep such as work stress and also family responsibilities to the unexpected challenges, such as illnesses, it is no wonder that your own quality sleep at night is sometimes elusive.

It is understandable that these might be something that you cannot be able to control, and eventually interfere with your sleep. Because of that, you might want to adopt certain habits that could encourage better sleep for yourself. This is because a good night’s sleep for everyone is just as important as regular exercise and also a healthy diet.

@dr.samhanTIPS UNTUK TIDUR LENA #PDPR #jombelajar #tiktokguru

♬ MONEY – 리사 (LISA)

Tips to have a good night’s sleep:

  1. Make sure that your bedroom is quiet, dark, and also cold (less than 30 degrees Celsius).
  2. Avoid eating 2 hours before sleep.
  3. Have a strict schedule on how long you should sleep every day (7-9 hours).
  4. Stop working 1 hour before sleep.
  5. Learn any technique to calm down before sleep such as some stretching or even meditating.
  6. Do not smoke, vape, or even drink alcohol.
  7. Do not drink caffeine or coffee 4-6 hours before sleep.

Sources: TikTok Dr. Samhan.

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